Pig ua pa kab mob yeej ib txwm yog ib tug complex kab mob uas plagues npua teb tswv.Lub etiology yog complex, cov kab mob muaj ntau haiv neeg, qhov kev nthuav dav yog dav, thiab kev tiv thaiv thiab kev tswj tsis yooj yim, uas ua rau kev poob zoo rau npua teb.Nyob rau hauv xyoo tas los no, npua ua liaj ua teb kab mob ua pa feem ntau muaj cov kab mob sib xyaw, yog li peb tau siv los hu ua npua ua pa ua pa.Cov kab mob muaj xws li Mycoplasma, Haemophilus parasuis, Actinobacillus pleuropneumoniae, pob ntseg xiav, circovirus thiab swine flu.
Rau kev tiv thaiv thiab kho cov kab mob ua pa, tilmicosin muaj txiaj ntsig zoo
Cov kab mob ua pa ntawm npua yog faib ua cov kab mob, kab mob thiab mycoplasma.Rau mycoplasma thiab porcine kis kab mob pleuropneumonia, cov tshuaj tua kab mob niaj hnub no tau tsim kev tiv thaiv, thiab cov tshuaj tua kab mob tshiab feem ntau tau txais kev kho mob los tiv thaiv thiab kho kab mob swine ua pa.Piv txwv li, tilmicosin, doxycycline, tyvalomycin, thiab lwm yam., ua ke nrog cov tshuaj tua kab mob hauv Suav teb, muaj txiaj ntsig zoo.Cov kev tshawb fawb tau pom tias tilmicosin muaj ib feem ntawm cov tshuaj tiv thaiv kab mob, thiab nws muaj txiaj ntsig zoo rau kev tswj cov kab mob porcine respiratory syndrome txuam nrog porcine PRRS.
Tilmicosinmuaj cov txheej txheem sib sib zog nqus thiab muaj ntau yam txiaj ntsig ntawm ob txheej txheej txheej.
Raws li peb txhua tus paub, tilmicosin yog ib qho tshuaj zoo tshaj plaws los tswj cov kab mob ua pa hauv npua teb.Txawm li cas los xij, cov teebmeem ntawm ntau yam tilmicosin ntawm kev ua lag luam tsis sib xws.Vim li cas qhov no?Peb yuav paub qhov txawv ntawm lawv li cas?Qhov txawv li cas?Rau tilmicosin, cov khoom siv raw yuav luag tib yam, thiab tsis muaj qhov sib txawv ntau.Txhawm rau cuam tshuam cov khoom siv, nws tsuas yog nyob ntawm nws cov txheej txheem tsim khoom.Hauv cov txheej txheem tsim khoom, siv zog ua kom zoo dua cov khoom siv tau dhau los ua qhov tseem ceeb.txoj kev loj hlob.
Siab zootilmicosin tshuajyuav tsum muaj plaub yam ntxwv: npua nyiam noj, kev tiv thaiv plab hnyuv, plab hnyuv plab thiab tso tawm qeeb.
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Paub qhov txawv ntawm qhov tsos
1. Cov tsis muaj coated tilmicosin hais yog zoo heev thiab yooj yim rau yaj nyob rau hauv chav tsev kub, thaum lub coated tilmicosin hais yog thicker thiab nyuaj rau yaj nyob rau hauv chav tsev kub.
2. Zoo tilmicosin (xws li Chuankexin coated nrog ob txheej microcapsules) muaj cov khoom sib xws thiab sib npaug.Feem ntau, cov khoom ntawm tilmicosin coated sib txawv ntawm qhov loj thiab sib xws.
Qhov txawv ntawm qhov saj hauv qhov ncauj (zoo palatability)
Tilmicosinsaj iab, thiab uncoated tilmicosin tsis haum rau kev tswj qhov ncauj.Tilmicosin nrog lub iab saj hauv lub qhov ncauj tsis tsuas yog ua tiav cov tshuaj tsis xav tau, tab sis kuj cuam tshuam rau kev noj zaub mov ntawm npua thiab ua rau muaj kev puas tsuaj loj.Tshuaj pov tseg.
Paub qhov txawv ntawm gastric solubility thiab enteric solubility
1. Cov txheej txheej ntawm tilmicosin muab faib ua enteric (acid-resistant tab sis tsis alkali-resistant) txheej thiab gastric-soluble (tsis acid- thiab alkali-resistant) txheej.Gastric-soluble (tsis resistant rau acid thiab alkali) coated tilmicosin yuav yaj thiab tso tawm los ntawm gastric acid nyob rau hauv lub plab, thiab thaum cov tshuaj tso tawm, nws yuav ua rau kom lub plab mucosa secrete gastric kua txiv, thiab cov kua gastric ntau heev yuav ua tau yooj yim. gastric los ntshav thiab gastric ulcers.Yog hais tias cov tshuaj yaj nyob rau hauv lub plab thiab tso tawm ua ntej, lub bioavailability ntawm cov tshuaj kuj yuav txo tau heev.Feem ntau, qhov ua tau zoo ntawm cov tshuaj yaj hauv plab yuav raug txo los ntawm ntau dua 10% piv nrog rau hauv cov hnyuv.Qhov no ua rau tus nqi tshuaj ntau ntxiv.
2. Cov txheej txheej enteric (anti-acid tab sis tsis anti-alkali) Cov txheej txheej tuaj yeem yaj thiab tso tawm los ntawm lub plab acid ib puag ncig insoluble hauv alkaline ib puag ncig ntawm txoj hnyuv, tiv thaiv ntau yam kev mob tshwm sim thiab cov tshuaj tiv thaiv cardiotoxic tshwm sim los ntawm kev tso tawm ntxov hauv plab.Nyob rau tib lub sijhawm, bioavailability ntawm cov tshuaj nyob rau hauv txoj hnyuv tau txhim kho.Kev tso tawm sai sai hauv cov hnyuv.
Cov txheej txheej Enteric siv cov txheej txheem sib txawv thiab cov txheej txheem, thiab kev tso tawm hauv cov hnyuv kuj txawv.Cov txheej txheem txheej txheem yog ib feem yaj thiab tso tawm hauv lub plab kab noj hniav thiab cov kua hauv plab, uas txawv heev los ntawm cov nyhuv ntawm ob txheej txheej microcapsule txheej, thiab qhov nqus ntawm cov hnyuv tau nrawm.
Post lub sij hawm: Mar-17-2022