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Cov tshuaj tua kab "kev nyab xeeb" tuaj yeem tua ntau dua li kab

Kev cuam tshuam rau qee yam tshuaj tua kab, xws li tshuaj yoov tshaj cum, muaj feem cuam tshuam rau kev noj qab haus huv, raws li kev soj ntsuam ntawm tsoomfwv cov ntaub ntawv tshawb fawb.
Ntawm cov neeg koom nrog hauv National Health and Nutrition Examination Survey (NHANES), qib siab dua ntawm kev raug siv tshuaj tua kab hauv tsev pyrethroid feem ntau cuam tshuam nrog kev pheej hmoo ntau dua ntawm cov kab mob plawv tuag (kev phom sij 3.00, 95% CI 1.02–8.80) Dr. Wei Bao thiab cov npoj yaig los ntawm University of Iowa hauv Iowa City qhia.
Cov neeg nyob rau hauv lub siab tshaj plaws tertile ntawm raug rau cov tshuaj tua kab no kuj muaj 56% nce kev pheej hmoo ntawm kev tuag los ntawm tag nrho cov ua rau piv nrog cov neeg nyob rau hauv lub qis tshaj plaws tertile ntawm raug rau cov tshuaj tua kab (RR 1.56, 95% CI 1.08–2. 26).
Txawm li cas los xij, cov kws sau ntawv sau tseg tias cov tshuaj tua kab pyrethroid tsis cuam tshuam nrog kev mob qog noj ntshav (RR 0.91, 95% CI 0.31–2.72).
Cov qauv raug hloov kho rau haiv neeg / haiv neeg, poj niam txiv neej, hnub nyoog, BMI, creatinine, kev noj haus, kev ua neej, thiab kev coj noj coj ua.
Pyrethroid insecticides tau pom zoo siv los ntawm US Environmental Protection Agency thiab feem ntau yog siv tshuaj yoov tshaj cum, tshuaj tua kab tsuag, tshuaj zawv plaub hau thiab tshuaj tsuag tsiaj, thiab lwm yam khoom siv tshuaj tua kab hauv tsev thiab sab nraum zoov thiab pom tias muaj kev nyab xeeb.
"Txawm hais tias muaj ntau tshaj li 1,000 pyrethroids tau tsim, tsuas muaj li ntawm ib lub kaum os pyrethroid tshuaj tua kab nyob rau hauv Teb Chaws Asmeskas lag luam, xws li permethrin, cypermethrin, deltamethrin thiab cyfluthrin," Bao pab neeg tau piav qhia, ntxiv tias kev siv cov pyrethroids tau "nce ntxiv.""Nyob rau hauv kaum xyoo tsis ntev los no, qhov xwm txheej tau hnyav zuj zus vim qhov kev tso tseg ntawm kev siv organophosphates hauv thaj chaw nyob.“
Hauv cov lus hais nrog, Stephen Stellman, Ph.D., MPH, thiab Jean Mager Stellman, Ph.D., ntawm Columbia University hauv New York, nco ntsoov tias pyrethroids "yog qhov thib ob feem ntau siv tshuaj tua kab hauv ntiaj teb, tag nrho ntau txhiab tus. kilograms thiab kaum pua ​​lab US dollars. "Kev muag khoom hauv Teb Chaws Asmeskas.“
Ntxiv mus, "cov tshuaj tua kab pyrethroid yog ubiquitous thiab raug inevitable," lawv sau.Nws tsis yog ib qho teeb meem rau cov neeg ua liaj ua teb nkaus xwb: "Aerial yoov tshaj cum los tswj tus kab mob West Nile thiab lwm yam kab mob los ntawm cov kab mob hauv New York thiab lwm qhov chaw cia siab rau pyrethroids," Stelmans sau ntawv.
Txoj kev tshawb no tau tshuaj xyuas cov txiaj ntsig ntawm ntau dua 2,000 tus neeg laus tuaj koom hauv 1999-2000 NHANES qhov project uas tau kuaj lub cev, sau cov ntshav, thiab teb cov lus nug tshawb fawb.Pyrethroid raug ntsuas los ntawm cov zis ntawm 3-phenoxybenzoic acid, pyrethroid metabolite, thiab cov neeg koom tau muab faib ua tertiles ntawm raug.
Thaum lub sij hawm nruab nrab ntawm kev soj ntsuam ntawm 14 xyoo, 246 tus neeg koom tau tuag: 52 los ntawm mob qog noj ntshav thiab 41 los ntawm kab mob plawv.
Qhov nruab nrab, cov neeg tsis yog neeg Mev dub tau pom ntau dua rau pyrethroids dua li Hispanics thiab cov neeg tsis yog neeg Mev.Cov neeg uas muaj nyiaj tau los qis dua, qib kev kawm qis dua, thiab kev noj zaub mov tsis zoo kuj tseem muaj qhov ua rau muaj kev cuam tshuam ntau tshaj plaws ntawm pyrethroid.
Stellman thiab Stellman tau hais txog "ib nrab-lub neej luv heev" ntawm pyrethroid biomarkers, qhov nruab nrab tsuas yog 5.7 teev.
"Lub xub ntiag ntawm cov qib kuaj pom tau sai sai ntawm cov metabolites pyrethroid tshem tawm hauv cov neeg loj, thaj chaw muaj ntau haiv neeg qhia tau tias muaj kev cuam tshuam mus ntev thiab tseem ua rau nws tseem ceeb los txheeb xyuas qee qhov chaw ib puag ncig," lawv tau sau tseg.
Txawm li cas los xij, lawv kuj tau sau tseg tias vim tias cov neeg koom nrog txoj kev tshawb fawb no tseem muaj hnub nyoog qis dua (20 txog 59 xyoo), nws nyuaj rau kev kwv yees qhov loj ntawm kev koom tes nrog kev tuag ntawm cov hlab plawv.
Txawm li cas los xij, "qhov kev pheej hmoo siab tsis zoo" ua rau muaj kev tshawb fawb ntxiv rau cov tshuaj no thiab lawv cov kev pheej hmoo rau pej xeem kev noj qab haus huv, Stellman thiab Stellman tau hais.
Lwm qhov kev txwv ntawm txoj kev tshawb no, raws li cov kws sau ntawv, yog kev siv cov tshuaj tso zis los ntsuas cov pyrethroid metabolites, uas yuav tsis cuam tshuam txog kev hloov pauv mus rau lub sijhawm, ua rau misclassification ntawm niaj hnub raug rau cov tshuaj tua kab pyrethroid.
Kristen Monaco yog tus kws sau ntawv laus tshwj xeeb hauv endocrinology, psychiatry thiab nephrology xov xwm.Nws nyob hauv New York chaw ua haujlwm thiab tau nrog lub tuam txhab txij li xyoo 2015.
Cov kev tshawb fawb tau txhawb nqa los ntawm National Institutes of Health (NIH) los ntawm University of Iowa Environmental Health Research Center.
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Post lub sij hawm: Sep-26-2023