Kev raug tshuaj tua kab, xws li cov tshuaj tua yoov, muaj feem cuam tshuam nrog cov teeb meem kev noj qab haus huv tsis zoo, raws li kev tshuaj xyuas cov ntaub ntawv tshawb fawb hauv tebchaws.
Ntawm cov neeg koom nrog hauv National Health and Nutrition Examination Survey (NHANES), cov tshuaj tua kab pyrethroid hauv tsev neeg uas siv ntau dua muaj feem cuam tshuam nrog kev pheej hmoo ntawm kev tuag los ntawm kab mob plawv peb npaug (hazard ratio 3.00, 95% CI 1.02–8.80) Dr. Wei Bao thiab cov npoj yaig los ntawm University of Iowa hauv Iowa City tau tshaj tawm.
Cov neeg uas muaj tertile siab tshaj plaws ntawm kev raug cov tshuaj tua kab no kuj muaj 56% kev pheej hmoo ntawm kev tuag los ntawm txhua yam ua rau piv rau cov neeg uas muaj tertile qis tshaj plaws ntawm kev raug cov tshuaj tua kab no (RR 1.56, 95% CI 1.08–2. 26).
Txawm li cas los xij, cov kws sau ntawv tau sau tseg tias cov tshuaj tua kab pyrethroid tsis muaj feem cuam tshuam nrog kev tuag ntawm mob qog noj ntshav (RR 0.91, 95% CI 0.31–2.72).
Cov qauv tau hloov kho rau haiv neeg/pab pawg neeg, poj niam txiv neej, hnub nyoog, BMI, creatinine, kev noj haus, kev ua neej, thiab cov yam ntxwv ntawm kev sib raug zoo hauv zej zog.
Cov tshuaj tua kab Pyrethroid tau txais kev pom zoo los ntawm US Environmental Protection Agency thiab feem ntau siv rau hauv cov tshuaj tua yoov tshaj cum, tshuaj tua ntshauv taub hau, tshuaj zawv plaub hau thiab tshuaj tsuag rau tsiaj, thiab lwm yam khoom tswj kab tsuag sab hauv tsev thiab sab nraum zoov thiab suav tias yog qhov muaj kev nyab xeeb.
"Txawm hais tias muaj ntau tshaj 1,000 hom tshuaj pyrethroids tau tsim tawm los, tsuas muaj li kaum ob hom tshuaj tua kab pyrethroid hauv Tebchaws Meskas, xws li permethrin, cypermethrin, deltamethrin thiab cyfluthrin," Bao pab neeg piav qhia, thiab ntxiv tias kev siv cov tshuaj pyrethroids tau "nce ntxiv." "Hauv xyoo caum dhau los no, qhov xwm txheej tau hnyav zuj zus vim yog kev tso tseg kev siv cov organophosphates hauv cov chaw nyob."
Hauv ib qho lus piav qhia nrog, Stephen Stellman, Ph.D., MPH, thiab Jean Mager Stellman, Ph.D., ntawm Columbia University hauv New York, sau tseg tias pyrethroids "yog cov tshuaj tua kab thib ob uas siv ntau tshaj plaws hauv ntiaj teb, tag nrho ntau txhiab kilograms thiab kaum tawm pua lab daus las Asmeskas." Kev muag khoom hauv Asmeskas hauv Asmeskas las. "
Ntxiv mus, "cov tshuaj tua kab pyrethroid muaj nyob txhua qhov chaw thiab kev raug tshuaj yog qhov tsis zam," lawv sau. Nws tsis yog teeb meem rau cov neeg ua liaj ua teb xwb: "Kev txau tshuaj yoov tshaj cum saum huab cua los tswj tus kab mob West Nile thiab lwm yam kab mob uas kis tau los ntawm cov kab mob hauv New York thiab lwm qhov chaw vam khom ntau rau cov tshuaj pyrethroids," Stelmans sau tseg.
Txoj kev tshawb fawb no tau tshuaj xyuas cov txiaj ntsig ntawm ntau dua 2,000 tus neeg laus koom nrog hauv qhov project NHANES xyoo 1999–2000 uas tau kuaj lub cev, sau cov qauv ntshav, thiab teb cov lus nug soj ntsuam. Kev raug tshuaj pyrethroid raug ntsuas los ntawm cov theem ntawm 3-phenoxybenzoic acid hauv cov zis, uas yog cov metabolite pyrethroid, thiab cov neeg koom nrog tau muab faib ua tertiles ntawm kev raug tshuaj.
Thaum lub sijhawm saib xyuas nruab nrab ntawm 14 xyoos, 246 tus neeg koom nrog tau tuag: 52 tus los ntawm mob qog noj ntshav thiab 41 tus los ntawm kab mob plawv.
Qhov nruab nrab, cov neeg dub uas tsis yog Hispanic raug tshuaj pyrethroids ntau dua li cov neeg Hispanic thiab cov neeg dawb uas tsis yog Hispanic. Cov neeg uas muaj nyiaj tsawg dua, kev kawm qis dua, thiab kev noj zaub mov tsis zoo kuj feem ntau raug tshuaj pyrethroid ntau tshaj plaws.
Stellman thiab Stellman tau hais txog "lub neej luv heev" ntawm cov cim qhia pyrethroid, qhov nruab nrab tsuas yog 5.7 teev xwb.
"Qhov muaj cov tshuaj pyrethroid metabolites uas raug tshem tawm sai sai hauv cov pej xeem loj thiab muaj ntau haiv neeg sib txawv qhia tau tias yuav raug tshuaj mus sij hawm ntev thiab ua rau nws tseem ceeb heev rau kev txheeb xyuas cov chaw ib puag ncig tshwj xeeb," lawv tau hais.
Txawm li cas los xij, lawv kuj tau sau tseg tias vim tias cov neeg koom nrog kev tshawb fawb no muaj hnub nyoog hluas dua (20 txog 59 xyoo), nws nyuaj rau kwv yees tag nrho qhov loj ntawm kev sib raug zoo nrog kev tuag ntawm cov kab mob plawv.
Txawm li cas los xij, "qhov kev pheej hmoo siab tshaj plaws" xav tau kev tshawb fawb ntxiv txog cov tshuaj no thiab lawv cov kev pheej hmoo rau kev noj qab haus huv pej xeem, Stellman thiab Stellman tau hais.
Lwm qhov kev txwv ntawm txoj kev tshawb fawb, raws li cov kws sau ntawv, yog kev siv cov qauv zis hauv daim teb los ntsuas cov metabolites pyrethroid, uas tej zaum yuav tsis qhia txog kev hloov pauv dhau sijhawm, ua rau muaj kev faib tsis raug ntawm kev raug tshuaj tua kab pyrethroid niaj hnub.
Kristen Monaco yog ib tug kws sau ntawv laus uas tshwj xeeb hauv kev kho mob endocrinology, kev puas siab puas ntsws thiab kev mob nephrology. Nws nyob hauv chaw ua haujlwm New York thiab tau ua haujlwm nrog lub tuam txhab txij li xyoo 2015.
Cov kev tshawb fawb tau txais kev txhawb nqa los ntawm National Institutes of Health (NIH) los ntawm University of Iowa Environmental Health Research Center.
Lub sijhawm tshaj tawm: Cuaj hlis-26-2023